Today is Wednesday, August 20, 2008


When this edition of Words To Live By was originally published, the links below opened active web pages.
Because many web sites discard or move content after a period of time, some links included here may no longer work.


New Page 1 January 11,2008
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News Headlines

Oral Minocycline Reduces Cetuximab-Associated Papular Rash
Alprostadil Soon After Prostatectomy Improves Return of Erectile Function

New Breast Cancer Screening Test Will Use Saliva
Docetaxel Treatment After Doxorubicin Cuts Breast Cancer Recurrence
Oophorectomy Ups Survival of Operable Breast Cancer in Premenopausal Women
Statins May Reduce Cancer Incidence in Older Patients

Disparities Continue in Cancer Treatment in U.S .
Severe Pain Warning Issued on Bisphosphonates
Saving Language After Brain Cancer Surgery

The Cost of Healthy Foods Going Up
Alemtuzumab Safe, Effective First-Line Treatment for Chronic Lymphocytic Leukemia
Cancer Patients, Doctors Talk Little of Emotions
Chemo, Tamoxifen Cut Risk of Second Breast Cancer
Adding Tipifarnib After Imatinib Failure in CML Restores Antitumor Efficacy
Cancer Patients Often Misinterpret Opioid Treatment a Sign of Imminent Death
Watchful Waiting OK for Some Lymphoma Patients
Benefit of Anthracyclines in Early Breast Cancer Limited to HER-Positive Disease
More Evidence Points to Anemia Drug Safety Problems

Cancerpage news is updated daily, Monday through Friday, and on the weekends as warranted.   Eighty-one new articles have been added to cancerpage news since the last newsletter last year.  To see ALL the latest stories, go to the cancerpage.com search page and click on Submit (but leave search field black.) 


Top Advances Against Cancer in 2007

The American Society of Clinical Oncology has just released its review of the top advances in cancer treatments,  screening, and prevention  in 2007. A total of 24 advances are reported in the latest report including the first systemic treatment for liver cancer, better treatments for kidney cancer, the appropriate use of MRI in breast cancer screening, the drop in HRT use tied to reduced incidence of breast cancers, the human papilloma virus (HPV) connection to head and neck cancer, the use of radiotherapy to control the spread of some lung cancers, and advances in the development and use of targeted therapies.  You can read the whole report online here. You can download a 5-minute podcast about the report here.


Government Moves Against Compounding Pharmacies

The Food and Drug Administration sent warning letters to 7 pharmacies  (located in California, Pennsylvania, Texas and Arizona) that offer compounded medications. The warnings were issued for ingredients used in and claims made for "bio-identical" Hormone Replacement Therapy (BHRT) that these pharmacies make on site. The FDA said by calling these products bio-identical, consumers might think that they are natural and superior to prescription HRT. In particular, several of the pharmacies were cited for  claims made on their web sites that their BHRT would protect against heart disease and breast cancer. In response, the International Academy of Compounding Pharmacists issued a blistering response, accusing the FDA of siding with big pharma and against women. "Millions of Americans have unique health needs that off-the-shelf prescription medicines cannot meet," the IACP said in the news release.


Doctors and Patients Cautioned

Bisphsphonates are sometimes prescribed to cancer patients to slow bone loss due to cancer or cancer treatments. These drugs are sold under the brand names Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa. Long-term use can lead to sometimes incapacitating pain in the bones, joints or muscles. The side effect, while mentioned in the drugs' indications, is often overlooked leading the FDA to issue an alert to doctors and consumers. "Healthcare professionals should consider whether bisphosphonate use might be responsible for severe musculoskeletal pain in patients who present with these symptoms and consider temporary or permanent discontinuation of the drug," the agency advises.   You can read more about the use of bisphosphonates in cancer by typing bisphosphonate in the search field here on cancerpage.

The FDA also warned doctors and patients about the growing clinical evidence that the incorrect use of some anti-anemia drugs in cancer can increase mortality and might even fuel cancer's growth. Read more  here on cancerpage, and here on the FDA site.


Top Science Stories

One of the most read science stories last year focused on the increased risk of developing advanced prostate cancer in men who take too many multivitamins.  The Journal of the National Cancer Institute reported on NCI research that showed that while multivitamin use has no impact on the risk of developing localized prostate cancer, taking too many raises the risk of advanced and fatal prostate cancer. You can re-read the story here


In the Lab

Constipation is a big problem for many cancer patients. Almost 90% of cancer patients taking opioid pain killers will develop "opioid-induced bowel dysfunction."  Doctors often urge patients to take steps like adjusting their diet and drinking more fluids to avoid what can develop into a life threatening condition. Patients may even stop taking their pain killers in an effort to get relief.  Now researchers are focusing on how to reduce the opioid's effect on the gastrointestinal tract without cutting pain relief. Two drugs, alvimopan and methylnaltrexone,  are currently in clinical trials and show promise.

Read more about controlling constipation during cancer treatment here on cancerpage.

 


The weekly cancerpage

The weekly cancerpage.com newsletter, Words To Live By, is intended for educational purposes only.
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